Daniel Kahne

Daniel Kahne is a Lecturer in the Department of Molecular & Cellular Biology at Harvard University. His research focuses on the biogenesis of the cell envelope in Gram-negative bacteria, particularly the mechanisms underlying outer membrane assembly and antibiotic resistance. His work explores how the outer membrane creates a permeability barrier that prevents many antibiotics from reaching their targets, with implications for repurposing existing drugs and discovering new antibiotics. The Kahne Lab investigates the machinery required for proper membrane assembly and the consequences of defects in this process. His research has been published in prominent journals such as Nature, Science, and the Journal of the American Chemical Society.